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高瓴重倉押注“心”賽道


更新日期:2021-02-03 14:44:19來源:網絡點擊:1717888
蘭蔻,蘭陵王妃,蘭陵王,貓和老鼠東北方言版,貓和老鼠中文版,貓和老鼠之海盜尋寶

ZAI1989NIANMEIGUOYALISANGNEIZHOUJUBANDEYICHANGXUESHUBAOGAOHUISHANG,DANSHENGLEGAIBIANRENLEIGUIJIDEYIXUEQIXIANG。ZHEYUANBENSHIYICHANGGUANYUGUANMOJIERUZHIJIADEXUESHUBAOGAO,DANQUEQIFALERUIDIANYISHENGAndersen,JIRANJINSHUZHIJIAKEYIJIEJUEGUANMOXUEGUANDEGAIHUAXIAZHAIWENTI,NEIMEZHUDONGMOBANMOXIAZHAIYINGGAIYEKEYIYONGTONGYANGDEYUANLIZHILIAO。

此后數年時間中,Andersen都在不遺余力的將這個奇想變成現實,但對于當時的醫學界來說,經導管主動脈瓣膜置換術(簡稱TAVI或TAVR技術)的理念還太過超前。Andersen曾向多家機構投稿換來的都是拒絕,但他并沒有放棄。

ZHONGYU,ZAIDIYIPIANGONGKAIFABIAODETAVRDONGWULINCHUANGYANJIUHOU,ZHEXIANGJISHUKAISHIHUODEXUESHUJIEDEGUANZHU,AndersenBUZAISHIGUJUNFENZHAN,DUONIANDEZHANYANHUODELEHUIBAO。

TAVRGAINIANDANSHENGSHINIANHOU,FAGUOYISHENGAlain CribierLVXIANJINXINGDONGWUSHIYAN,BINGZAILIANGNIANHOUDE2002NIANWANCHENGSHOULIRENTISHIYAN,ZHEXIANGDIANFUXINGJISHUDEKEXINGXINGZHONGYUBEIZHENGSHI。

ZAIGUOQU,XINZANGBANMOJIBINGHUANZHEJINNENGYIKAOKAIXIONGSHOUSHUDEFANGSHIZHILIAO,RANERZHEZHONGZHILIAOFANGANFENGXIANJIDA,QIEBUSHIYONGYUZHONGDUHUANZHE。TAVRDEYIYIZAIYURANGHUANZHEYOULEWEIHAIGENGXIAO、FENGXIANGENGDIDEZHILIAOFANGAN。

數據顯示,心臟瓣膜疾病依然是全球高發的疾病之一,2019年全球共有2.13億心臟瓣膜疾病患者,導致260萬人死亡。目前全國TAVR的適用人群接近430萬人,而作為更優治療方案的TAVR技術滲透率卻僅為0.3%,遠低于世界平均的4.5%。

XIANERYIJIAN,ZHONGGUOTAVRSHIYIGEJIJUQIANLIDESHICHANG。YOUQIBANSUISHEHUILAOLINGHUADEJIAJU,XINZANGBANMOJIBINGHUANZHERENSHUZHENGYURIJUZENG。

ZAIXINTONGYILIAO(02160.HK)2YUE4RIDULISHANGSHIHOU,ZHONGGUOTAVRXINGYEDEZHUYAOWANJIAYIJINGXISHUDENGLUZIBENSHICHANG。YINGSHOUWEIZUYIYUANDEQINGKUANGXIA,XINTONGYILIAOJIUHUODELEJIN280YIYUANDESHIZHI,SHICHANGDUIQICHONGMANXINXIN。

CHUXINTONGYILIAOSHANGSHIBEISHOUZHUIPENGWAI,QIMINGYIYAOHEPEIJIAYILIAOZAOYICHENGGONGRUXUANSHOUPINARUGANGGUTONGDEBLEIYIYAOGU。

GENGRANGTOUZIZHECEMUDESHI,ZAIQIMINGYILIAO、XINTONGYILIAO、PEIJIAYILIAOBEIHOU,DOUNENGKANDAOGAOLINGZIBENDEYINGZI。JIUJINGGAOLINGWEIHERUCIKANHAOTAVRZHEGESAIDAONI?YUSANJIAZHONG,SHUIYOUNENGGOUBAWOZENGCHANGJIYUCHENGWEIXINGYELINGTOUYANGNI?JINTIANWOMENJIULAISHENDUPOUXIJINGDAOGUANBANMOZHILIAO(JIANCHENGTVT)ZHEGELANHAISAIDAO。

01 藍海賽道

ZUOWEIYIXIANGDANSHENGJINERSHINIANDEJISHU,ZHENGGETVTXINGYEMUQIANRENGCHUYUXINXINGJIEDUAN,WEILAIYIDUANSHIJIANNEIRENGJIANGBAOCHIGAOSUZENGCHANGZHISHI。

TVTSHIDANGXIAZUIWEIXIANJINDEYIZHONGXINZANGBANMOJIBINGZHILIAOFANGFA。DUIYUXINZANGBANMOJIBINGHUANZHEERYAN,KEYIXUANZEYAOWUYUSHOUSHULIANGZHONGFANGFAZHILIAO,QIZHONGYAOWUSHUYUZHIBIAOBUZHIBEN,SHOUSHUSHIYENEIJIAOWEIPUBIANDEXUANZE,YESHILIAOXIAOZUIHAODE。

ANZHAOSHOUSHUZHONGLEIDEBUTONG,XINZANGBANMOJIBINGSHOUSHUKEFENWEISANDALEI,FENBIESHICHUANTONGKAIXIONGSHOUSHU、WEICHUANGBANMOSHOUSHU、TVTSANZHONG。QIZHONG,TVTZUOWEIZUIXIANJINDEJISHU,YUQITALIANGZHONGSHOUSHUXIANGBI,LIAOXIAOXIANGFANGDANQUEGENGJIAANQUAN。ZHEZHONGLIAOFAYIJINGBEIYINGYONGYUYUELAIYUEDUODEZHONGDUHUANZHE,HUOGAOJINGZHIRENQUN。

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XINZANGBANMOJIBINGGONGFENWEISIDALEI:ZHUDONGMOBANMO、ERJIANBAN、SANJIANBAN、FEIDONGMOBANMO。LIYONGTVTJISHUMUQIANGONGKEYIZHIYUZHUDONGMOBANMOXIAZHAI、ERJIANBANFANLIU、SANJIANBANFANLIU、FEIDONGMOBANFANLIUSIZHONGJIBING,SIZHONGZHILIAOFANGFAFENBIEBEICHENGZUO:JINGDAOGUANZHUDONGMOBANZHIHUANSHU(JIANCHENGTAVR)、JINGDAOGUANFEIDONGMOBANZHIHUANSHU(JIANCHENGTPVR)、JINGDAOGUANERJIANBANZHIHUANSHU(JIANCHENGTMVR)、JINGDAOGUANSANJIANBANZHIHUANSHU(JIANCHENGTTVR)。

CONGSIZHONGJISHUSHIYONGRENQUNLAIKAN,TMVRHETTVRZAIZHONGGUODEHUANZHESHUCHUYUQIANWANJI,TAVRHUANZHESHUGANGDADAO430WAN,ERTPVRDESHULIANGJIAOSHAO。

目前,TAVR和TPVR已經實現商業化,但也僅處于初級階段,而TMVR和TTVR領域尚無任何一款產品獲批。由于TPVR市場份額過小,因此各家都將TAVR作為突破重點,而份額更大的TMVR和TTVR市場,則是遠期爭奪的對象。

就目前最成熟的TAVR而言,其市場滲透率也并不高。2019年中國共進行了2400例TAVR手術,滲透率僅約0.3%。對于中國的心臟瓣膜疾病患者而言,TAVR手術的最大阻礙是過高的費用,傳統開胸手術的費用約5-6萬元,而TAVR手術的全部成本則在30萬左右。

盡管價格不菲,但TAVR滲透率的提升已經成為必然。一方面,人口增長和社會老齡化讓心臟瓣膜疾病的患者群體不斷增長;另一方面,生活水平的提高也讓TAVR手術成本逐漸被更多人接受。此外,對于很多重度患者來說,傳統手術開胸風險極大,而TAVR則成為了唯一的治療方案。

ZONGHEYISHANGZHEXIEYINSU,SUIZHUHUANZHEDUITAVRSHOUSHUJIESHOUDUDETISHENG,ZHEYIXINGYEDEGAOZENGCHANGHONGLIQIJIANGCHIXUHENCHANGYIDUANSHIJIAN。TONGYANGDELUOJIYESHIYONGYUTMVRHETTVRSHICHANG。

02 寡頭格局

JINGUANTVTXINGYECAIGANGGANGQIBU,DANJILIEDEJINGZHENGQUEYIJINGZAIYANFAJIEDUANZHANKAI。

XIANJIEDUAN,TVTWANJIAJINGZHENGDEJIAODIANZHUYAOZAITAVRSHICHANG,TONGSHIGEJIAYEZAIWEIGENGDADETMVRHETTVRQIANZAISHICHANGXULI。ZONGTILAIKAN,TAVRCHANPINYINGXIANGQIYEDUANQIYEJI,ERTMVRHETTVRCHANPINZEJUEDINGQIYECHANGQIJIAZHI。

MUQIAN,ZHONGGUOTAVRSHICHANGGONGYOU4KUANCHANPINWANCHENGSHANGYEHUA,FENBIEWEIQIMINGYILIAODE VenusA-Valve、SUZHOUJIECHENGDEJ-Valve、XINTONGYILIAODEVita FlowYIJIAIDEHUASHENGMINGDESapien 3。CIWAIHUANYOUPEIJIAYILIAODETaurusOne、QIMINGYILIAODEVenusA-Plus、XINTONGYILIAODEVitaFlow II BAOCHAN,PEIJIAYILIAODETaurusEliteHEJINSHISHENGWUDEProstyleCHUYULINCHUANGYANFAZHONG。

注:TF(經股動脈)、TA(經心尖)、SE(自膨脹式)、BE(球囊膨脹)、BP(牛心包)、PP(豬心包)

ANZHAOXINBANMOJINRUDIANDEBUTONG,TAVRKEFENWEIJINGXINJIANHEJINGGUDONGMOLIANGZHONG,JINGGUDONGMOSHANGHAIJIAOXIAO,WEIHUANZHESHOUXUAN,JINGXINJIANSHUYUKAIXIONGSHOUSHU,CHUANGSHANGJIAODA;ANZHAOPENGZHANGJIZHIBUTONG,TAVRKEFENWEIZIPENGZHANGSHIHEQIUNANGSHIPENGZHANG,QIUNANGSHIPENGZHANGSHIFANGDEGONGXIAOGENGGAO;ANBANMOCHAYI,KEFENWEIZHUXINBAOYUNIUXINBAO,NIUXINBAOCAIZHIDEBANMOGENGJIANAIYONG。CIWAI,SUIZHUXINGYEFAZHAN,KEHUISHOUXING、WAIBUMIFENGQUN、DIANDONGSHOUBINGJUNSHITAVRFAZHANDEFANGXIANG。

RUGUOBUKAOLVYANFACHENGBEN,NEIMEZUILIXIANGDETAVRBANMOYINGYOUJINGGUDONGMOJINRU,JINXINGQIUNANGSHIPENGZHANGDENIUXINBAOBANMO,TONGSHIHUANJUBEIKEHUISHOUXING、WAIBUMIFENGQUN、DIANDONGSHOUBINGDENGTEXING。

YIJINGSHANGYEHUADE4KUANCHANPINZHONG,J-ValveSHIDIYIKUANSHANGSHIDETAVRCHANPIN,JUBEIXIANFAYOUSHI,DANYOUYUQICAIYONGJINGXINJIANDEXUEGUANRULU,ZAISHOUKUANGUDONGMOCHANPIN VenusA-ValveSHANGSHIHOU,J-ValveHENKUAIJIUSHIQULESHICHANGJINGZHENGLI。2019NIANDUSHUJUXIANSHI,VenusA-ValveCHUYUZHONGGUOTAVRXINGYETONGZHIDIWEI,SHICHANGZHANYOULVJIEJINBACHENG。

SHIJISHANG,VenusA-ValveHEJ-ValveDOUSUANSHIZHONGGUODIYIDAITAVRCHANPIN,SUIZHUXINTONGYILIAOHEAIDEHUASHENGMINGDERUJU,RUJINDETAVRXINGYEYIJINGMIANLINSHENGJIHUANDAI。

03 新一輪洗牌

ZAIDIERDAITAVRJINGZHENGZHONG,QIMINGYILIAO、XINTONGYILIAO、AIDEHUASHENGMING、PEIJIAYILIAODOUJIANGZHIJIECANYUJINGZHENG。

QIMINGYILIAODEDIERDAICHANPINVenusA-PlusYIJINGHUOPI,JIJIANGKAIZHANSHANGYEHUAYUNYING。CONGJISHUJIAODUKAN,VenusA-PlusJIAOYIDAIZHUYAOSHITIANJIALEKEHUISHOUGONGNENG,YIDANCHUXIANFANGZHIBULIXIANGDEQINGKUANG,RANGYISHENGKEYIHUISHOUJINXINGERCIFANGZHI,TISHENGLESHOUSHUDEWENDINGXING。DANQIYIRANCAIYONGZHUXINBAOBANMOHEZIPENGZHANGFANGSHI,YUJINGZHENGDUISHOUXIANGBIBINGBUZHANYOU。

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從目前來看,心通醫療的兩代產品無論是性價比還是技術層面,都具備行業革新者的潛質。

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04 高瓴意不在當下

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XIANGGUAN:

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相關熱詞搜索:蘭蔻,蘭陵王妃,蘭陵王,貓和老鼠東北方言版,貓和老鼠中文版,貓和老鼠之海盜尋寶

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